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Genes: convenient tokens of our time

My post today, perhaps typically cranky, was triggered by an essay at Aeon about the influence that the film Still Alice has had on thinking about Alzheimer's Disease (AD). As the piece puts it, AD is presented in the film as a genetic disease with a simply predictable doom-like known genetic cause.  The authors argue that the movie is more than entertainment.  It's a portrayal that raises an important ethical issue, because it is very misleading to leave the impression that AD is a predictable genetic disease.  That's because a clear genetic causation, and thus the simple 'we can test for it' representation, applies only to a small fraction of AD.  The film badly misrepresents the overall reality of this awful form of the disease (a good treatment of Alzheimer's disease and its history is Margaret Lock's thoughtful The Alzheimer Conundrum, 2013, Princeton Press).

While focusing on AD, the Aeon piece makes strong statements about our obsession with genes, in ways that we think can be readily generalized.  In a nutshell, genes have become the convenient tokens of our time.

Symboling is a key to making us 'human'
If there is any one thing that most distinguishes our human species from others, it may be the use of language as a symbolic way to perceive the world and communicate to others.  Symboling has long been said by anthropologists to be an important key to our evolution and the development of culture, itself based on language.

Symbol and metaphor are used not just to represent the world and to communicate about it, but also to sort out our social structure and our relationships with each other and the world.  Language is largely the manipulation or invocation of symbols.  In a species that understands future events and generalities, like death and sex, in abstract terms, the symbols of language can be reassuring or starkly threatening.  We can use them to soothe ourselves or to manipulate others, and they can also be used in the societal dance around who has power, influence, and resources.

Symbols represent a perception of reality, but a symbol is not in itself reality.  It is our filter, on or around which we base our interactions and even our material lives.  And, science is as thoroughly influenced by symbols as any other human endeavor.

Science is, like religion, a part of our culture that purports to lead us to understand and generalize about the world, but because science is itself a cultural endeavor, it is also part and parcel of the hierarchy and empire building we do in general, part of a cultural machinery that includes self-promotion, and mutually reinforcing service industries including news media, and even scientific journals themselves.

The current or even growing pressures to maintain factory-like 'productivity' in terms of grants coming in and papers going out is largely at odds with the fundamental purpose of science (as opposed to 'technology').  Unlike designing a better product, in the important, leading-edge areas of science, we don't know where we're going.  That is indeed the reason that it is science.  Exploring the unknown is what really good science is about.  That's not naturally an assembly-line process, because the latter depends on using known facts.  However, our society is increasingly forcing science to be like a factory, with a rather short-term kind of fiscal accountability.

Our culture, like any culture, creates symbols to use as tokens as we go about our lives.  Tokens are reassuring or explanatory symbols, and we naturally use them in the manipulations for various resources that culture is often about.  Nowadays, a central token is the gene.

DNA; Wikipedia

Genes as symbols
Genes are proffered as the irrefutable ubiquitous cause of things, the salvation, the explanation, in ways rather similar to the way God and miracles are proffered by religion.  Genes conveniently lead to manipulation by technology, and technology sells in our industrial culture. Genes are specific rather than vague, are enumerable, can be seen as real core 'data' to explain the world.  Genes are widely used as ultimate blameworthy causes, responsible for disease which comes to be defined as what happens when genes go 'wrong'.  Being literally unseen, like angels, genes can take on an aura of pervasive power and mystery.  The incantation by scientists is that if we can only be enabled to find them we can even cure them (with CRISPR or some other promised panacea), exorcising their evil. All of this invocation of fundamental causal tokens is particulate enough to be marketable for grants and research proposals, great for publishing in journals and for news media to gawk at in wonder. Genes provide impressively mysterious tokens for scientists to promise almost to create miracles by manipulating.  Genes stand for life's Book of Truth, much as sacred texts have traditionally done and, for many, still do.

Genes provide fundamental symbolic tokens in theories of life--its essence, its evolution, of human behavior, of good and evil traits, of atoms of causation from which everything follows. They lurk in the background, responsible for all good and evil.  So in our age in human history, it is not surprising that reports of finding genes 'for' this or that have unbelievable explanatory panache.  It's not a trivial aspect of this symbolic role that people (including scientists) have to take others' word for what they claim as insights.

This token does, of course, have underlying reality
We're in the age of science, so that it is only to be expected that we'll have tokens relevant to this endeavor.  That we have our symbols around which to build other aspects of our culture doesn't mean that the biology of genes is being made up out of whole cloth.  Unlike religion, where things can be 'verified' only by claims of communication with God, genes can of course, at least in principle, be checked and claims tested.  Genes obviously do have major and fundamental roles in life.  If that isn't true, we are really misperceiving fundamentals of our existence.  So, even when complexities of causation are daunting, we can claim and blame what we want on genes and in a sense be correct at least at some level.  That enhances and endorses the token value of genes.

Genes do have great sticking power.  The Aeon piece about AD is just one of countless daily examples.  A fraction of cases of AD are so closely associated with the presence of some known variants in a couple of genes, that true causation--whatever the mechanism--seems an entirely plausible explanation.  Likewise, there are hundreds or thousands of disorders that seem clearly to be inherited and as the result of malfunction of one or two specific genes.  The cultural extension of this in our society that we are stressing here is the extension of these clearly causative findings to the idea that causation can be enumerated in convenient ways mainly by peoples' inherited genomes and that other aspects of biological causation are often treated as being rather superficial or incidental.  That in a sense is typical of deeply held cultural icons or tokens.

The problem with genes as tokens is that they are invoked generally or generically in the competition for cultural resources, material and symbolic.  Personally, we think there are issues, genetic issues in fact, that deserve greater investment, rather than just the easier to invoke bigger-is-better approach. They include a much more intense attack on those many traits that we already know without any serious doubt are tractably genetic--due to one or only a couple of genes, and therefore which real genetic therapy might treat or prevent effectively.  By contrast, most traits even if they are affected by genetic variation as all traits must be, are predominantly due to environmental or chance causative factors.  We have ways to avoid many diseases that don't require genetic approaches, but as vague entities they're perfect subjects for invoking the gene token, and policy in the industrial world clearly shows this.

Some progress does of course occur because of genetically-based research, but the promise far outpaces the reality of genetic cures.  But genes are the material tokens that keep the motor running far beyond the actual level of progress.  They effectively reflect our time--our molecular, computer, technological culture imagery, our love of scale, size and the material grandeur they generate.

Every culture, every generation has its tokens and belief systems.  Genes are among ours.  They're never perfect.  People seek hope, and what velvet robes and gilded cathedrals and mosques provide for many, whereas the humming laboratories do for a growing number of others.

Tokens, symbols and metaphors: they drive much of what people do, even in science.

Please send me your Intro BioAnth (PhysAnth, Human Origins/Evolution) syllabus

Dear colleagues,

I'm in the early stages of planning a study to determine the most effective approaches to teaching Introductory Biological/Physical Anthropology (also called "Human Origins" etc...) to undergraduates.

Mostly I'm interested in their evolutionary thinking and whether we can identify our best methods for bettering it over one semester.

This study would involve inviting students enrolled in this course at colleges and universities around North America to take pre- and post-tests on-line (which could earn them some form of extra credit on your end, if you do that sort of thing). All participation would be entirely anonymous except for the feedback about your own (anonymized first) students that you and I share, if you'd like to hear about it. The results of this study should benefit us all.

Before I get to any of it, though, it would help greatly to see your syllabi so that I can identify the major ways that our learning outcomes and our approaches vary. This will help me frame hypotheses and write survey questions.

So please, I'm begging you, please send me your most recent syllabus for Introduction to Biological Anthropology (aka Introduction to Physical Anthropology aka Introduction to Human Evolution/Origins) or the equivalent course at your institution, that you teach.

holly_dunsworth@uri.edu

If you want mine in return, I'll be happy to reciprocate!

If you do share, you have my word that I will keep your syllabus confidential and anonymous and will not share with anyone.

When you send it, would you please mention whether you'd be interested in participating in such a study in the near future?

Thank you so much in advance,
Holly

P.S. If you could share this with your colleagues who teach this course, I'd be forever grateful.

One mermaid's path to tenure

I’m not writing this in hopes that you’ll congratulate me. This is just meant to give readers a peek behind the curtain.

I’m writing because maybe you, or maybe someone who has sway over your career, has read an academic's blog and wondered how it would affect their chances for tenure. Or, maybe you or a colleague, your chair or department head, your dean, or your provost has wondered why anyone would bother going to the trouble to write on a blog when there are more important things to accomplish. Well, in my case, there clearly weren’t, because I managed to write on this blog and still be awarded tenure. What's more, I know, without a doubt, that my writing on this blog was integral to it.
Not me and not Proconsul.
This is the seriously awesome result of googling for "Mermaid Professor." (source)

I’ve written about why I blog before. And, looking back, there is so much more I could add to that post because of what's occurred over time since. However, the main reason still stands: Writing on The Mermaid’s Tale has been immensely important for my academic life. The reading and writing I do here enhances my teaching and research and the enlightening discussions I participate in here and elsewhere (facilitated by my writing here) boost my teaching and research even more.  And the people who make the decisions about my tenure definitely noticed. My departmental colleagues, my dean, and the provost all readily acknowledged the value of my blogging in their letters recommending me for tenure. And the good people who served as my external reviewers didn't see my blogging as damning enough to withhold their support. And the good... no, great people who collaborate with me certainly never turned up their noses either!

I've known since receiving the provost's letter that I owe it to readers and other bloggers to post something about getting tenure. I also thought a tenure-related post could help out younger academics, in general, by exposing how someone who's never taught in a graduate program--with all the intellectual buzz and the worker bees to help, you know, the academic model us Ph.D.s are most familiar with--can still get awarded tenure.

But I've been dreading such a post because I really don't want to write a biography right now. It feels quite narcissistic to get tenure and then to post your life story as if tenure somehow validated that, as if anyone could possibly emulate another person's detailed path to tenure, as if anyone would want to!

Plus, where to begin? So much so deep in my past has set me up for getting awarded tenure, so many people have been crucial to this outcome, that it's impossible to know where or with whom to start except, obviously, at conception.

But what I really don't feel like writing about publicly, and in association with hooray-for-tenure, is about why I haven't done much work on early Homo despite studying with a terrifically wonderful advisor, Alan Walker, to do just that. And that's because part of the reason is a statistic here. That, as well as other parts of the explanation take away from the fact that I'm very happy with the way my career has panned out and I continue to look very much forward to every single day I'm an anthropologist.

So instead of a tour through my influenced and circumstantial history leading up to tenure, maybe I'll post the narratives I included in my portfolio. It's going to be uncomfortable. I'm going to have to look away while I paste the text, like I do when the phlebotomist pricks my vein. But here you go, minus the files of evidence that go along with each narrative.* This is a successful tenure portfolio at a small state school, in an undergraduate-only program. Hope it's useful because ouch it feels quite personal:

Tenure Portfolio Narratives
Statement of Teaching and Learning
I’ve taught four different courses so far at URI and they all focus on human origins, evolution and variation. The introductory course, APG 201: Human Origins, counts as a general education requirement for the natural sciences and also is a requirement for majors and minors in anthropology. The upper level courses attract not just anthropology majors and minors but students from diverse scholarly backgrounds who are interested in the in-depth examination of issues in biological anthropology. These upper level courses include: APG 300: The Human Fossil Record (a hands-on course which is why I dedicated a large portion of my start-up funds to the purchase of new fossil casts which augmented the existing collection); APG 310: Sex and Reproduction in Our Species (a course I created because of my new research interests in the evolution of human reproduction, as well as in procreative beliefs and how they have influenced human evolution.); APG 350: Human Variation (in which I will continue to use personal genomics to engage students.). In all of these courses, my two most important teaching goals are:

(1) Students should get as strong a handle on evolution as possible, shedding as many misconceptions as possible, so that they can best comprehend the biological, ecological, and cultural significance of human variation and evolution. (That, in a nutshell, is why human evolution is taught and studied within an anthropological context!)

(2) Students should achieve as much of this evolutionary and anthropological understanding on their own as possible, by thinking creatively, synthetically, and critically about the evidence.

Number one means that I probably take more time with evolutionary theory than most of my colleagues at other institutions. But because biological anthropology is the only college-level exposure to evolution (let alone biology) that many undergraduates have, it’s important that it's strong. Once they graduate, they’re consuming, producing, and voting based in no small part on their understanding of their place in nature and their (and others') place in the human species. This one chance that we get to represent evolutionary theory and human ecology and biology is crucial make-or-break time for us anthropology professors. Number two means that I have to deviate far from the conventional format for the introductory course.

In January 2012, I was awarded a $21,842.50 from the Provost’s Office under their initiative called “Innovative Approaches Using Technology to Enhance the Student Experience at URI”. The title of my proposal, “145 URI undergraduates peer into their genomes to trace their ancestries, discover their individualities, ponder their futures, and celebrate their unified humanity,” sums up nicely what students were able to do. It has been a transformative new curriculum on many planes, from my perspective as a teacher, from student perspectives as learners, and also for the impact it is making on how my colleagues in my field and beyond will use personal genomics to teach anthropology. That is why I will continue to use personal genomics in APG 350.

I'm always updating APG 201, every semester, with new findings in human evolutionary biology and physical/biological anthropology. I'm also always modifying pedagogy and adapting activities with the goals of improving and broadening student learning. For example, I use colored index cards (in lieu of clickers) for regularly practicing questions with immediate feedback, which seem to engage and motivate students in new ways. I also used personal genomics in this course when I awarded the Provost’s grant, however, I plan to only use it in the upper level course (APG 350) in the future, not because it wasn’t a success, but because it takes up too much time away from fundamentals that need to be covered in this introductory course.

Since arriving at URI, I have dramatically rearranged the traditional presentation of APG 201 course materials (as they are presented in every major textbook for this popular Gen Ed course in North America) and have taught it for three years in this new way with great success. The major difference is that I start with active observations and then work on explaining them with evolutionary theory rather than beginning with evolutionary theory and then asking students to apply it thoughtlessly to spoon-fed information. Starting in Spring 2015, I will begin teaching it without a textbook, using two excellent popular science books and many on-line high-quality readings instead. The syllabus for this new curriculum is included in my portfolio. I will provide essential, fundamental material in handouts when it is not covered explicitly in the readings—something I’ve been poised to do since I wrote a reference/textbook Human Origins 101 in 2007. I plan to eventually publish a paper describing this new strategy of guiding who I call “naturalists in a molecular age.” Because word has gotten out to my colleagues about both the personal genomics as well as this new curriculum, I’ve been invited to participate in an education symposium (that’s been accepted) at this year’s physical anthropology meetings in March 2015.

One of the most positive outcomes of the first run of APG 310: Sex and Reproduction in Our Species was the recruitment of a student (name withheld, Anthropology and Chemistry major, class of 2014) to take on a project in APG 470: Directed Research with me, guided by constructive input from the whole class. He updated a survey from a 1960s Master’s thesis at URI that looked into “premarital sexual behavior” of undergraduates here at URI. After earning IRB approval to administer the survey to volunteer participants, he presented his research at the end of the Spring 2014 semester to a group of students and faculty. Most interesting was the result showing no significant difference in the amount of premarital sexual behavior that male and female students reported, as opposed to the significant difference between the sexes that the first survey found, decades ago. This sort of work piques student interest and two anthropology majors from my second-run of APG 310, name withheld and name withheld, have worked with original student name withheld to rewrite the survey to bring it up to date, to be more health-focused, and in hopes of making the results more instructive to the URI community. Name withheld and name withheld will be submitting their proposal to the IRB committee in October 2015 and if approved they’ll be collecting the data and analyzing it over the course of the academic year.

I have been very lucky that some of the most enthusiastic researchers and clever minds have opted to work on projects with me for credits in APG 470. I asked name withheld (Anthropology & Biology) to co-author an article on the evolution of childbirth with me for the Annual Reviews of Anthropology because of her research skills and also her relevant interests as demonstrated in prior anthropology courses with me. And then name withheld (Anthropology & Biology) has gotten a head start on her Honors project with me already. She’s taken up a project that I’ve been wanting to get started since 2006. She’s figuring out how apes lost their tails and, thus, why we ended up tailless. In the coming academic year, she’ll be applying for funding to travel to regional museums to collect data on primate skeletons.

In the next few years, I will be devising short courses and field trips through the study abroad office to sites of anthropological interest—not just to my fossil field sites in Kenya, but to other sites in Africa, Europe, and Latin America where students can chase primates in the wild or crawl into painted Paleolithic caves.

Statement of Research
How did humans become humans, how did apes? How does evolution work? And does it work differently in humans or because of humans? These are the questions that drive my research and educational endeavors. Since arriving in Fall 2011, URI has encouraged and supported my scientific and scholarly activity as I have pursued two main areas of research (below). I have also begun a book project that brings all of these things together. These three research areas should continue to challenge me and create opportunities for students for many years to come.

1. Augmenting and making sense of the fossil record for ape and human evolution.
As part of an international and interdisciplinary team, funded by the Leakey Foundation and the NSF, I perform paleoanthropological fieldwork on Rusinga and Mfangano Islands in Western Kenya. Fossils from these sites represent plants and animals that lived in the early Miocene epoch (dating to about 20-18 million years ago), some of which, like the primate Proconsul, are good candidates for some of the earliest apes. Without the origin of apes, chimpanzees and humans would not have occurred. This work is not only geared toward finding more specimens of Proconsul and other primates, but we are also reconstructing the paleoenvironments in which these primates lived and evolved. Our latest paper to come of this project was published in Nature Communications this year.

Here at home, I continue to work on the functional anatomy and growth and development (ontogenetic) patterns of fossil apes like Proconsul, particularly in their feet and hindlimbs, as those traits relate to locomotion and to the ability to cling to mother during development, and over evolutionary time. It’s important to reconstruct how this fossil ape was moving about if we’re to understand how modern ape and human behavior came about. Since coming to URI I have taken advantage of our proximity to the primate skeletal collections at the American Museum of Natural History where I have gathered data on extant primates to compare against the fossils. Up until recently this work has been a continuation of my doctoral dissertation on anthropoid feet and hindlimbs, but recently I have begun a similar project with undergraduate anthropology/biology major and honors student name withheld on tails. By looking to primates in the fossil record (like the tailless Proconsul), to variation in extant primate tails, and to known genes for tail development, we are answering the question, “Why don’t humans have tails?”

Although there’s much to keep us busy in addressing these matters here in the U.S., I would still like to return semi-regularly to Kenya to continue the lifetime of work that needs to be done at Rusinga and Mfangano Islands, in both fossil collection and analysis. I hope to create a short course with International Programs to give URI students a marvelous experience doing paleoanthropology.

2. Reconstructing the evolution of human pregnancy, childbirth, and infant development
Living apes, not just fossils, also offer a glimpse of evolution. So along with another team of collaborators, I study energy use in apes and other mammals. Mammals process energy differently from one another and these differences may reflect different evolutionary selection pressures both internally within the organism and externally from the environment. Energetic use in humans is fairly well understood but it's only through comparison with other species that we can understand human energetics from an evolutionary perspective. Likewise, human data are necessary for understanding the energetic use of other primates. To this end, I’ve collected energetic and behavioral data from the chimpanzees and gorillas at Lincoln Park Zoo. The first paper to come of this work was published this year in PNAS.

I am particularly interested in the energetics and metabolic parameters of pregnancy, fetal growth, infant growth, and lactation and how those determine the timing of birth in humans and other mammals. This is a significant area of anthropological research, given how it has long been assumed that the unique human skeleton, particularly the pelvis and how it’s metamorphosed for upright walking, has limited gestation and fetal growth—that the skeleton explains why our babies are difficult to birth and are quite helpless when they arrive. My research has shown that this traditional pelvic explanation (the “obstetrical dilemma”) is much weaker than its popularity indicates and that maternal metabolism and how mothers process energy are likely to be the primary determinants of gestation length and fetal growth, not just in humans but across primates and placental mammals. Although it is my primary goal to reconstruct human evolutionary history as accurately as possible (or at least as plausibly as possible), there are also potential applications of this research toward better understanding the causes of pregnancy disorders like preeclampsia.

This research has attracted attention and I have been invited to give talks at numerous college campuses as a result. The highlight so far has been the invitation from organizers (and established human reproduction researchers) Karen Rosenberg and Wenda Trevathan to participate in a scholarly seminar at Santa Fe’s School for Advanced Research (SAR) titled “Costly but cute: How helpless babies made us human.” The collection of our papers is currently under peer-review and the volume should be published next year. I’ve also been invited to write on the evolution of childbirth for the Annual Reviews of Anthropology. That manuscript is due in January 2015 and I’ve enlisted a keen undergraduate anthropology/biology major, name withheld, to co-author the piece with me.

I am currently scheming up my next research steps. (The rest of this paragraph is redacted because it's a big fun secret for now.) 

The Baby Makers: Scholarly/Popular Trade Book Project
For the last two years I’ve been working with a literary agent on a proposal for a book that I’m very excited about. It’s requiring me to scratch at the overlap between evolutionary biology and cultural anthropology—disciplines that are diametrically opposed in the eyes of many scholars. Reconciling these two schools of thought as well as discovering what, perhaps, evolutionary biology cannot explain is challenging but feels necessary in order for me to go on as both an anthropologist and an educator. The book assumes, as its premise, that ... (The rest is redacted because it's a big fun secret for now. It's a project that I've since partnered-up with Anne in, and we'll gladly talk about it but not post much about yet. We're very excited and having a ball.)

Statement of Service and Professional Outreach
I have participated in service projects at many levels at URI and within my field, while I have also prioritized outreach, locally and beyond. I will continue to perform these duties and hope to increase my contributions and impact, but here is what I have done so far:

Our department had a successful search for a new colleague and I’m proud to have been on the committee that helped to accomplish it. In addition to our regular advising majors and minors, I served as the anthropology advisor at University College for the 2013-14 academic year. The same year I joined the Faculty Senate and I served on name withheld’s Master’s committee in CELS where he defended a stellar thesis on shark feeding morphology. This year I served on the search committee for a multicultural postdoctoral fellow in BES/CELS chaired by name withheld.

Beyond URI, I have reviewed manuscripts for several scientific and scholarly journals, as well as grant proposals for NSF and the Leakey Foundation. In 2013, Nature Education launched the room of open-access, peer-reviewed articles on The Human Fossil Record, which I edited as part of their Biological Anthropology series. There are even more articles in press that will be posted soon. In addition, I was invited to give a talk at the California Academy of Sciences in November 2012 about my experience with personal genomics (23andMe) as an educator, as an anthropologist, and as a human being. While I was in San Francisco I visited an assembly of 3-8 graders as well as a high school genetics class and talked with them about science, genetics, paleoanthropology, and evolution. There, I also gave a presentation to the Leakey Foundation’s Scientific and Executive Boards about the research I’ve done that they’ve funded and will hopefully continue to support. It was well received and I was encouraged to keep applying for funding. Here in Rhode Island I have presented on evolution at a public library, a Masonic lodge, a Catholic elementary school, and three times at assisted living/retirement homes.

For the past three years I have been a core team member of the Smithsonian Institution National Museum of Natural History’s Human Origins Program Educator’s Network (HopEdNet). My duties include fielding questions about human evolution, via email, that visitors to the exhibit hall in Washington DC type into the computer. I’m also involved with the Smithsonian in a magnificent project called “Teaching Evolution Through Human Examples” (or “TetHE”) which is led by PIs name withheld and name withheld of the Smithsonian’s Human Origins Program. I have helped to create new resource activities and teaching strategies focused on human evolution for AP Biology. My primary role is as scientific content consultant but I am part of a larger group of people, including the leaders of the AP Biology standards as well as pedagogy experts, all working together on this project. These curricular packets will be complete in date withheld and I am very much looking forward to using them in APG 350: Human Variation, both to teach biological anthropology but also to expose our students to this pedagogy should they become educators themselves. It’s through my TetHE colleagues that I got my scientific process lesson plan published at Berkeley’s Understanding Science site. It’s currently one of the top three teacher resources there.

I try very hard, where and when I can, to engage the greater public in anthropology, evolution, and science and so I continue to write on the blog The Mermaid’s Tale. I write about new discoveries in biological anthropology, including my own, as well as educational issues (mainly for my colleagues), and larger “how do we know what we know” questions. This is most definitely an outreach endeavor, however, the boost to my own research and teaching that comes from writing here, and engaging with my blog’s co-authors and colleagues who read the blog, is significant. A list of my best, most popular posts is here. In total, my posts have received 110,000 hits since I began writing in 2009. Most of my posts are read by hundreds, but a few have been seen by as many as 13,000+ because some colleagues assign them to students (as do I) and others have cited or re-published them on their own websites. My most recent post on natural selection was republished by the on-line science magazine io9. Another of my posts was re-published on Scientific American’s site. It’s due in part to my activity on my blog that my anthropological research got noticed by the BBC and I was asked to be part of an episode of their science program Horizon (equivalent to our Nova). Here’s the piece in the Guardian that discusses my research and that was published to announce this television program. I also filmed all about ape and human tail loss for PBS’s “Your Inner Fish” program: “How do we know when our ancestors lost their tails?”

***
Do you have questions? Anonymous or otherwise, feel free to post here or on Facebook or Twitter and I'll do my best to answer them. Cheers.


*Here's my CV and here's my scholar.google profile. In the above narratives, you may see some new typos because I've just copied and pasted them from a pdf and also because I make typos. Hyperlinks are gone because they're not the point, and I replaced all names with "name withheld" because Google searches for those people shouldn't land on this.

This year's textbook-free Introduction to Biological Anthropology course

The cost of living is ridiculous, but one nice thing about living so close to the beach (besides the beach) is that the semester begins after Labor Day. Many of our students move into vacation homes when the season ends. So although many of you are scrambling to write your syllabi for an August start, we have a bit longer to wallow in procrastination here. It's August, the Sunday of the year.

Since syllabi are on our minds, I thought I'd share mine, once again, because I've changed it, once again.

I get bored reading the same books and I'm ever-hopeful that I can improve my courses. Both of those things mean there's always serious work to be done on the teaching spectrum of this job--something that flies in the face of advice for securing tenure. But what good is that advice if teaching is valued at your institution? And what good is that advice when it's given to a lifelong learner who just cannot imagine heeding it? (I may answer these questions in an upcoming post about my path to being awarded tenure.)

Anyway, this year in APG 201: Human Origins (Introduction to Biological Anthropology; a requirement for majors and a general education course in the natural sciences), we're reading Your Inner Fish again, but we're replacing Paleofantasy with The Incredible Unlikeliness of Being. There is no textbook for good reason. And, as a bonus, students will only spend up to about 30 bucks total on materials.

Yes, I'm sort of chums with, and rather fond of, both books' authors, especially IUB's. But so what? These are fantastic books and complement beautifully not only one another but, most importantly, the material I cover in the classroom.

There will be three quizzes and a research project (focusing on information literacy) that add up to 50% of the course and a notebook that makes up the other 50%. The notebook has all the classroom notes that students take (imperative) and includes their hand-written daily assignments (yes, there are daily assignments) based on the assigned readings/viewings/activities.

Sure, it seems like a lot of grading. There are 120 students in this class, but I  assure you that I am not insane. Number one: I tried the notebook experience last semester and it was hard work but it was manageable. Number two: If I can't teach at a small liberal arts college, I can still act like I do. Students deserve that experience. And so do I.  The grading robots help out with the quizzes (mostly multiple-choice), but otherwise, it's up to me. I don't nit-pick with my red pen, at least not always. They just have to complete the notebook, but very thoughtfully and professionally so, to get credit. But I think it's a much much richer experience if they are encouraged to read along and to think along like this, on their own. And a great way to improve independent reading, writing, and thinking is to have them do it regularly, habitually--just like with sports. Detailed feedback or not, they will improve on these fronts just by practicing them, or they will fail the course for not doing the work. Don't come to practice, get cut from the team. It's so simple, yet so incredibly difficult for far too many with a high school diploma.

Anyway, here's the plan. If it helps you out, I'm honored. If you do something similar it would be encouraging if you could let me know (like if you use no textbook, or if you have them produce a notebook, or if you too rearrange the order of the material, which runs counter to every textbook, all of which put natural selection and genetics right up front and absolutely ruin the evolution learning experience to my mind, as I've written before). The headings for each day (see below) describe that day's lecture/discussion topic and there aren't always readings that address those specifically! I provide quite a bit of information in the form of handouts when that's the case. Also, I have more readings listed here than one might expect for an introductory level, general education course. The saying goes that students should spend three hours outside class for every hour inside class. And I agree. I also think it's a tragedy and, worse, a financial scam (some are $100k in debt... for a state school!) if they're not challenged enough to do much work outside of class. Some of the readings listed are there for students who need help understanding lecture or who missed lecture. That is, some of the readings can be skipped if students are present and engaged with lecture, which draws heavily on them. Of course, the readings that the assignments rest on cannot be skipped. And, of course, my questions based on the readings will improve each semester. Enough rambling, though. Here's the plan:

APG 201: Human origins

Unit 1. OBSERVE. This view of life. Our place in nature.
Big questions: What is the anthropological perspective? What is the scientific approach to understanding human origins? What is a human? What are human traits? How do humans fit on the Tree of Life? What is evolution?

1.1  – Introduction to course* 
*I used to do Dog Origins with my dog, as a metaphor for what we were about to do with humans, but my dog is getting too old and frail and I've got this beautiful new baby so I'm going to use my baby instead and talk about his development and theirs, etc...to set up both the books and the lectures to follow. I don't pass out the syllabus until the end of this first day. We go over it on the second day of class.
Notebook Assignment
·        In-class writing assignment ("What is evolution?")

1.2 – Overview of course
Reading/viewing
·        IUB, Chapter 1: Beginnings - Roberts
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.

1.3 – Doing Biological Anthropology                                                 
Reading/viewing
·        What is it like to be a biological anthropologist? A Field Paleontologist's Point of View – Su (Nature Education)
·        Notes from the Field: A Primatologist's Point of View – Morgan (Nature Education)
·        Expedition Rusinga (video; 8 min) https://www.youtube.com/watch?v=4y1puNyB9e8   
·        The ape in the trees – Dunsworth (The Mermaid’s Tale)
·        How Do We Know When Our Ancestors Lost Their Tails? (video; 4 min)
Notebook Assignment
·        In a half-page or more: Why do humans study biological anthropology? And also, why take this course? Be as objective or as personal as you would like with your answer.

1.4 – Scientific process
Reading/viewing
·        How Science Works (video; 10 min):
·        Understanding science: How Science Works, pages 1-21; starts here:
·        Carl Sagan’s Rules for Critical Thinking and Nonsense Detection
·        10 Scientific Ideas That Scientists Wish You Would Stop Misusing
Notebook Assignment
·        Scientific Process worksheet - Located at end of syllabus
·        Osteology and comparative anatomy worksheet - Located at end of syllabus

1.5 – Linnaeus and the Order Primates – NOTEBOOK CHECK
Reading/viewing
·        IUB, Chapter 2: Heads and brains – Roberts
·        Characteristics of Crown Primates – Kirk (Nature Education)
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.
·        Primate Expert worksheet - Located at end of syllabus

1.6 – Primate taxonomy
Reading/viewing
·        IUB, Chapter 3: Skulls and senses – Roberts
·        Many primate video clips –Posted on Sakai
·        Old World monkeys – Lawrence and Cords (Nature Education)
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.
·        In a half-page or more: Write about your primate video viewing experience, for example, you might write about what you saw, at face value, or you might want to write about what defied your expectations or what surprised you, or what you would like to learn more about.

1.7 – Locomotion and encephalization         
Reading/viewing
·        IUB, Chapter 4: Speech and gills - Roberts
·        Many primate video clips –Posted on Sakai
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.
·        In a half-page or more: Without looking at any resources except for these films, come up with some categories for the different types of primate locomotion, give those categories names and definitions, and list which species in the films fall into which categories you’ve created.

1.8 – Tool use and communication
Reading/viewing
·        IUB, Chapter 5: Spine and segments – Roberts
·        The Human Spark 2 (video; 55 mins)
·        Primate locomotion – Gebo (Nature Education)
·        Primate Communication – Zuberbuhler (Nature Ed)
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.
·        In a half-page or more: Reflect on The Human Spark 2, highlighting something you already knew and also something you learned that was brand new to you. What is the human spark?

1.9 - Diet
Reading/viewing
·        IUB, Chapter 6: Ribs, lungs and hearts– Roberts
·        IUB, Chapter 7: Guts and yolk sacs – Roberts
·        Peace Among Primates – Sapolsky (The Greater Good)
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapters and be sure to include what it’s got to do with human evolution.
·        In a half-page or more: Reflect meaningfully on the article by Sapolsky, relating it to your life is fine but not required.

1.10 - Sociality
Reading/viewing
·        IUB, Chapter 8: Gonads, genitals and gestation – Roberts
·        What Influences the Size of Groups in Which Primates Choose to Live? – Chapman & Teichroeb (Nature Ed)
·        Primate Sociality and Social Systems – Swedell (Nature Ed)
·        Primates in communities – Lambert (Nature Ed)
Notebook Assignment
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.

1.11 – Evolution and Darwin’s Evidence
Reading/viewing
·        Two chapters from The Autobiography of Charles Darwin: "Voyage…" (p. 71-81 ) and "An account of how several books arose" (p. 116- 135)
Notebook Assignment
·        In a half-page or more: What circumstances or experiences influenced Darwin's thinking?

1.12 - Phylogeny
Reading/viewing
·        Reading a phylogenetic tree – Baum (Nature Ed)
·        Trait Evolution on a Phylogenetic Tree – Baum (Nature Ed)
Notebook Assignment
·        Phylogeny worksheet - Located at end of syllabus

1.13 – The modern evidence that Darwin wishes he had
Reading/viewing
·        YIF, Chapter 1: Finding Your Inner Fish - Shubin
·        Amazing Places, Amazing Fossils: Tiktaalik (video; 5 mins)
·        YIF, Chapter 2: Getting a Grip - Shubin
·        The Ancient History of the Human Hand (video; 4 mins)
·        IUB, Chapter 9: On the nature of limbsRoberts
Notebook Assignment
·        In a half-page or more: What does Shubin mean by "your inner fish"? What's the connection between a fish’s fin and your hand? How could you falsify evolutionary theory?
·        In a half-page or more:  Reflect on Roberts’ chapter and be sure to include what it’s got to do with human evolution.

1.14 – Quiz 1– NOTEBOOK CHECK


Unit 2. EXPLAIN and PREDICT. Explaining the similarities and differences. How evolution works.
Big Questions: Why are we like our parents but not exactly? Why are we like other species but not exactly? How did human traits and human variation evolve? How do we know what the last common ancestor (LCA) was like?

2.1 – Inheritance and gene expression, 1
Reading/viewing
·        YIF, Chapter 3: Handy Genes - Shubin
·        YIF, Chapter 4: Teeth Everywhere - Shubin
·        The Evolution of Your Teeth (video; 3 mins) https://www.youtube.com/watch?v=ohq3CoOKEoo
·        YIF, Chapter 5: Getting ahead - Shubin
·        Our Fishy Brain (video; 2.5 mins) http://video.pbs.org/video/2365207797/
·        Developing the Chromosome Theory – O’Connor (Nature Ed)
·        Genetic Recombination – Clancy (Nature Ed)
·        What is a Gene? Colinearity and Transcription Units – Pray (Nature Ed)
·        RNA functions – Clancy (Nature Ed)
Notebook Assignment
·        In a half-page or more: What did you learn about how to do paleontology from the Shubin chapters? What does he mean by your "inner shark"?

2.2 – Inheritance and gene expression, 2
Reading/viewing
·        YIF, Chapter 6: The Best-Laid (Body) Plans - Shubin
·        YIF, Chapter 7: Adventures in Bodybuilding – Shubin
·        Hox Genes in Development: The Hox Code – Myers (Nature Ed)
·        Gregor Mendel and the Principles of Inheritance – Miko (Nature Ed)
·        Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders – Chial (Nature Ed)
·        Phenotypic Range of Gene Expression: Environmental Influence – Lobo & Shaw (Nature Ed)
·        Genetic Dominance: Genotype-Phenotype Relationships – Miko (Nature Ed)
·        Pleiotropy: One Gene Can Affect Multiple Traits – Lobo (Nature Ed)
·        Polygenic Inheritance and Gene Mapping – Chial (Nature Ed)
Notebook Assignment
·        In a half-page or more: What are Hox genes and, according to Shubin, what do they have to do with linking a fruit fly to you? What is one benefit to being a sponge?

2.3 – Mutation and gene flow
Reading/viewing
·        YIF, Chapter 8: Making Scents - Shubin
·        YIF, Chapter 9: Vision - Shubin
·        Finding the Origins of Human Color Vision (video; 5 mins)
·        YIF, Chapter 10: Ears - Shubin
·        We Hear with the Bones that Reptiles Eat With (video; 4 mins)
·        Evolution Is Change in the Inherited Traits of a Population through Successive Generations – Forbes and Krimmel (Nature Ed)
·        Mutations Are the Raw Materials of Evolution – Carlin (Nature Ed)
Notebook Assignment
·        In a half-page or more: After reading the Shubin chapters… Is it fair to say that when you smell something, that something is touching your brain? Why is it called the eyeless gene if you can have it and still have eyes? How does hearing work? What does your ear do besides hear, and how? What does drinking lots of alcohol do to your ears?
·        Scenario building assignment - Located at end of syllabus

2.4 – Genetic drift
Reading/viewing
·        Neutral Theory: The null hypothesis of molecular evolution – Duret (Nature Ed)
·        Things Genes Can’t Do – Weiss and Buchanan (Aeon)
Notebook Assignment
·        In a half-page or more: Reflect meaningfully on the Weiss and Buchanan article and highlight something that you already knew, but also the things that you learned that are brand new to you.

2.5 – Natural selection
Reading/viewing
·        Negative selection – Loewe (Nature Ed)
·        On the mythology of natural selection. Part I: Introduction – Weiss (The Mermaid’s Tale)
·        On the mythology of natural selection. Part II: Classical Darwinism– Weiss (The Mermaid’s Tale)
·        Secrets of Charles Darwin’s Breakthrough -  Bauer (Salon)
·        Natural selection, genetic drift and gene flow do not act in isolation in natural populations – Andrews (Nature Ed)
·        Sexual selection – Brennan (Nature Ed)
Notebook Assignment
·        Wisdom Teeth worksheet - Located at end of syllabus

2.6 – Malaria resistance and lactase persistence
Reading/viewing
·        Natural Selection: Uncovering Mechanisms of Evolutionary Adaptation to Infectious Disease – Sabeti (Nature Ed)
Notebook Assignment
·        In a half-page or more: How can natural selection explain the prevalence of sickle cell anemia?

2.7 – Building evolutionary scenarios
Reading/viewing
·        Evolution is the only natural explanation – Dunsworth (The Mermaid’s Tale)
·        The F-words of Evolution  – Dunsworth (The Mermaid’s Tale)
·        Another F-word of evolution  – Dunsworth (The Mermaid’s Tale)
·        Mutation not natural selection drives evolution –  Tarlach (about Nei; Discover Magazine)
Notebook Assignment
·        Drift vs. Selection worksheet - Located at end of syllabus
·        Looking back at scenario building assignment - Located at end of syllabus

2.8 – Species and speciation
Reading/viewing  
·         Why should we care about species? – Hey (Nature Ed)
·        Speciation: The origin of new species – Safran (Nature Ed)
·        The maintenance of species diversity – Levine (Nature Ed)
·        Macroevolution: Examples from the Primate World – Clee & Gonder (Nature Ed)
·        Primate Speciation: A Case Study of African Apes – Mitchell & Gonder (Nature Ed)
Notebook Assignment
·        In a half-page or more: What are some hypotheses for how or why the African apes, including humans, diverged? Why might genetic divergence and species divergence not occur in sync?

2.9 – Genomics, molecular clocks, and the LCA
Reading/viewing  
·        The Onion Test – Gregory (Genomicron)
·        The Molecular Clock and Estimating Species Divergence – Ho (Nature Ed)
·        Lice and Human Evolution (video; 11 mins) http://video.pbs.org/video/1790635347/
Notebook Assignment
·        Speciation and molecular clocks worksheet - Located at end of syllabus

2.10 – Quiz 2 – NOTEBOOK CHECK


Unit 3. TEST. Evolving humans, past and present. Ancient evidence for our extinct hominin relatives. Modern human origins and variation. The cultural controversy over evolution.
Big Questions: How did human traits evolve? How and why do humans vary? Should we look to our ancestors as a lifestyle guide? Are we still evolving? Why is human evolution misunderstood and why is it controversial?

3.1 – Fossils, geology, and dating methods
Reading/viewing
·        Planet without apes? – Stanford (Huffington Post)
·       How to Become a Primate Fossil – Dunsworth (Nature Ed)
Notebook Assignment
·        In a half-page or more: What could lead to a future on Earth without apes? What kinds of evidence would such a process leave behind for future humans to use for explaining why apes went extinct?

3.2 – The primate fossil record; Origins of bipedalism
Reading/viewing
·        Dating Rocks and Fossils Using Geologic Methods – Peppe (Nature Ed)
Notebook Assignment
·        Geology worksheet - Located at end of syllabus

3.3 – Sahelanthropus, Orrorin, Ardipithecus - NOTEBOOK CHECK
Reading/viewing
·        Desktop Diaries: Tim White (video; 7 mi– Posted on Sakai)
·        Ancient Human Ancestors: Walking in the woods (video; 4 mins)
·        Lucy (video; 5 mins) https://www.youtube.com/watch?v=m8Lkk6u-wQM
·        Trowelblazers (blog): http://trowelblazers.tumblr.com/
·        An Unsuitable Job for a Woman (blog): http://www.ellencurrano.me/blog/
·        Overview of hominin evolution – Pontzer (Nature Ed)
·        The Earliest Hominins: Sahelanthropus, Orrorin, and Ardipithecus - Su (Nature Ed):
Notebook Assignment
·        In a half-page or more: Go to each of the blogs above (Trowelblazers and An Unsuitable…), choose one woman from each and briefly discuss her contribution to scientific knowledge of the world.

3.4 – Australopithecus and Paranthropus
Reading/viewing
·        Lucy: A marvelous specimen – Schrein (Nature Ed)
·        The "Robust" Australopiths – Constantino (Nature Ed)
·        In a half-page or more: Describe something monumental (either for paleoanthropology or for you personally) to be learned or realized thanks to Lucy.

3.5 – The first stone tool makers and Homo habilis
Reading/viewing
·        Ancient Hands, Ancient Tools (video; 5 mins) https://www.youtube.com/watch?v=5_ew9J8lpwo
·        A Primer on Paleolithic Technology – Ferraro (Nature Ed)
·        Evidence for Meat-Eating by Early Humans – Pobiner (Nature Ed)
·        Archaeologists officially declare collective sigh over “Paleo Diet”
Notebook Assignment
·        In a half-page or more:  What are the academic criticisms of the paleo diet? Can you name something at the grocery store that could count as "paleo"? Why did I ask this question?

3.6 – Homo erectus
Reading/viewing
·        Homo erectus - A Bigger, Smarter, Faster Hominin Lineage – Van Arsdale (Nature Ed)
Notebook Assignment
·        In a half page or more: Make the case for Homo erectusbeing our species’ direct ancestor, as opposed to a more distant relative like the robust australopiths/Paranthropus.

3.7– Neanderthals
Reading/viewing
·        Archaic Homo sapiens – Bae (Nature Ed)
·        What happened to the Neanderthals? – Harvati (Nature Ed)
·        Neanderthal Behavior – Monnier (Nature Ed)
Notebook Assignment
·        In a half-page or more: What happened to the Neanderthals?

3.8 - Anatomically modern Homo sapiens - RESEARCH PROJECT DUE
Reading/viewing
·        The Transition to Modern Behavior – Wurz (Nature Ed)
Notebook Assignment
·        the printed parts of the Research Project will go here for day 3.8

3.9 – Models of human origins and geographic dispersal
Reading/viewing
·        The Neanderthal Inside Us (video; 4 mins)
·        Anthropological genetics: Inferring the history of our species through the analysis of DNA – Hodgson & Disotell (Evolution: Education and Outreach)
·        Testing models of modern human origins with archaeology and anatomy – Tryon & Bailey (Nature Ed)
·        Human Evolutionary Tree – Adams (Nature Ed)
·        Paternity Testing: Blood Types and DNA – Adams (Nature Ed)
Notebook Assignment
·        In a half-page or more: Choose two models for human origins and dispersal and compare and contrast them.

3.10 -  Race and evolution’s P.R. problem
Reading/viewing
·        From the Belgian Congo to the Bronx Zoo (NPR)
·        A True and Faithful Account of Mr. Ota Benga the Pygmy, Written by M. Berman, Zookeeper – Mansbach
Notebook Assignment
·        In a half-page or more: Why was Ota Benga brought to the U.S.? Why was Ota Benga brought to the Bronx Zoo? Regarding issues that Ota Benga’s story raised, what do religious and evolutionary perspectives have in common? Why doesn’t a story like Ota Benga’s take place today?

3.11 – Skin pigmentation
Reading/viewing
·        Understanding Race: http://www.understandingrace.org/
·        In the Name of Darwin – Kevles (PBS) http://www.pbs.org/wgbh/evolution/darwin/nameof/
·        Human Skin Color Variation (NMNH): http://humanorigins.si.edu/evidence/genetics/skin-color
·        Human Races May Have Biological Meaning, But Races Mean Nothing About Humanity – Khan (Discover blogs)
·        Are humans hard-wired for racial prejudice?  - Sapolsky (LA Times)
Notebook Assignment
·        Peruse the whole Understanding Race site then take the quiz and prove that you completed it by listing the correct answers. (just letters is fine)
·        In a half-page or more: Why is evolution controversial?

3.12 – The cultural controversy over evolution
Reading/viewing
·        Does Evolutionary Theory Need a Rethink? (Nature)
·        You'd have to be science illiterate to think "believe in evolution" measures science literacy –Kahan (The Cultural Cognition Project)
·        Even Atheists Intuitively Believe in a Creator – Jacobs (Pacific Standard)
·        We are not the boss of natural selection – Dunsworth (io9)
Notebook Assignment
·        In a half page or more: Why is evolution controversial?
·        In a half-page or more: Are we still evolving? Why did I ask this question?

3.13 – Building evolutionary scenarios
Notebook Assignment
·        Revise your research project essay to make it excellent
·        In a half-page or more: After re-reading the essay you wrote in class on Day 1.1 ("What is evolution?") compose a letter to yourself highlighting what you were right about and what you were wrong about or what was incomplete about your answer based on what you learned this semester.

3.14 - Quiz 3

3.15 – Conclusion to course – NOTEBOOK CHECK
Reading/viewing
·        YIF, Chapter 11: The Meaning of It All – Shubin
·        IUB, The Making of Us - Roberts
·        Evolution reduces the meaning of life to survival and reproduction... Is that bad? – Dunsworth (The Mermaid’s Tale)
Notebook Assignment
·        In a half-page or more: Briefly describe what you learned this semester. And, reflect on what you're still left wondering and how you could find the answers to your remaining questions.
·        In a half-page or more: Can an evolutionary perspective have a positive impact on someone’s life? Explain why you answered yes or no.

Final Exam Time Slot: No final exam: Instead, discuss notebook and course with Dr. Dunsworth and receive grade in person between 8 am-noon today in Chafee 132.

Extra credit!!! Make a time machine then go back to the start of the semester, attend classes, take notes, read all of the things, think about all of the things, complete the assignments, and study for the quizzes.














Rare Disease Day and the promises of personalized medicine

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